This grows the line longer one bar at a time. For that we use the current bar number ( bar_index). The first is the line to change ( monthClose). To do so we call the t_x2() function with two arguments. When the current bar is not the chart’s last ( not barstate.islast), then we make the line longer by updating the time coordinate of its second point. This if/else statement extends the line in two ways. t_x2(id =monthClose, x = bar_index)Įlse t_xloc(id =monthClose, x1 = time , There extend the line 5 days in the future. Extend the line with one bar, each bar. That line we made is, however, quite small: its drawn between the previous and current bar. We put the line reference that line.new() returns in the monthClose variable. We make the line orange ( color.orange) and thicker than normal ( width=2). Since this code runs on the first bar of the month, that previous close is last month’s close. For its price we use the previous bar’s close ( close). We draw the line between the previous ( bar_index) and current bar number ( bar_index). When that happens, we want to make a new trend line at the close of the previous month. That variable has such a value when the current bar is the first of the calendar month. This if statement sees if sinceStart equals ( =) zero ( 0). X2 = bar_index, y2 = close, color = color.orange , ![]() MonthClose : = line.new(x1 = bar_index, y1 = close , Make a new line at the start of each month if (sinceStart = 0) Of course, the opposite is also possible: switch a line from time values to bar numbers. With xloc=xloc.bar_time we set the line to use time values. So this code moves the line’s second point 24 hours in the future. That big value is the number of milliseconds in a single day. The second point is set to the bar’s opening time ( time) plus 86,400,000. We set the line’s first point to 25 bars back ( x1=time). ![]() Then we want to use a different type of time coordinate. We put the line reference in the myLine variable for use next. To get those values we use the bar_index variable. That line uses the default bar numbers for its time coordinates. This code snippet first makes a trend line with the line.new() function. Switch the line to use time values instead // (makes it possible to draw line in the future) t_xloc(id =myLine, x1 = time , MyLine = line.new(x1 = bar_index, y1 = close , Make a new trend line (defaults // to using `xloc.bar_index`) Here’s how that works with the t_xloc() function: But now something happened and we want to move the line to the right of the current bar (meaning, into the future). Now let’s see how we can use the function. ![]() # Quick examples: the t_xloc() function in practice In those cases, when we want to switch how existing trend line is positioned, we use TradingView’s t_xloc() function. But then in real-time use time values so we can draw the trend line in the future. We might for instance position a trend line with bar numbers on historical bars. Sometimes a line should switch from one x-axis format to another. That capability is enough 90% of the time. When we execute the line.new() function to make a new trend line, we can immediately specify if that line should use bar numbers ( xloc=xloc.bar_index) or time values ( xloc=xloc.bar_time). # When to use TradingView’s t_xloc() function? We can adjust the line’s prices, update its time coordinates, and change both the price and time coordinates. Published by Elsevier B.V.There are a few other ways to change a line’s coordinates. GDH1 LncRNA Pancreatic cancer XLOC_006390 c-Myc.Ĭopyright © 2019. Therefore, XLOC_006390/c-Myc may be a potential target for PC, and its abnormal activation also indicates the progression of PC. The dysregulated lncRNA/c-Myc axis increased glutamate metabolism, promoting PC progression to a higher stage. Clinically, XLOC_006390 was positively correlated with the mRNA level of GDH1, and c-Myc positively regulated GDH1 gene expression, which was tightly associated with PC patient prognosis. Overexpression of XLOC_006390 promoted the protein stability of c-Myc by blocking its ubiquitination. Downregulation of GDH1 mRNA levels by XLOC_006390 deletion could be rescued by overexpression of c-Myc. ![]() c-Myc binds to the promoter of GDH1 and activates its transcription. Therefore, we first screened transcription factors targeting the GDH1 gene promoter and confirmed that c-Myc regulates GDH1 transcription. We subsequently confirmed that the decrease in aKG was mainly due to the downregulation of glutamate dehydrogenase 1 (GDH1) at the mRNA level. Our study found that alpha-ketoglutarate (aKG) levels were significantly reduced in the absence of XLOC_006390. The role of lncRNAs in the regulation of glutamate metabolism and metabolic reprogramming of pancreatic cancer (PC) during nutrient deprivation is largely unknown.
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